RESPIT® was founded by Jon Plant, DVM, DACVD, who has over 30 years of experience as a veterinary dermatologist. During his career, he has held positions in academia, industry, and private dermatology referral practice. He continues to practice veterinary dermatology at SkinVet Clinic in Lake Oswego, Oregon, USA.

Traditionally, immunotherapy has been customized for each pet using allergy test results as a starting point. However, test results may be affected by seasonality, patient preparation, technique, subjective scoring, and the choice of laboratory (for serum testing) or dermatologist (for intradermal testing). False positive and false negative reactions occur with both testing methods.